Discovery in 2012 of a unique antibody that protects against both influenza A and B viruses. The team of Robert Friesen in the Crucell Vaccine Institute discovered one additional antibody, somewhat like the one discovered in 2009, but with one…
Discovery in 2012 of antibodies specifically protecting against influenza B infections. In 2012 a team led by Robert Friesen in the Crucell Vaccine Institute in close collaboration with Ian Wilson’s group at the Scripps Institute described and characterized two antibodies…
Discovery in 2011 of the target of the second most important group of influenza viruses. On August 12, 2011 Science published our report “A Highly Conserved Neutralizing Epitope on Group 2 Influenza A Viruses”. The crystal structure of this new…
Discovery in 2008 of the target for human monoclonal antibodies highly conserved among one group of yearly returning and some pandemic influenza viruses (Throsby, PLOS One, 2008). This target was subsequently defined by co-crystallography of the antibody- antigen complex (Ekiert,…
Discovery in 2007 of a prototype tuberculosis vaccine based on Ad35 intended to be used both in children and adults who either received or did not receive BCG (Radosevic, Infect Immun, 2007). A first hint of a correlate of protection…
